A few quotes from a fascinating new book, Collaborative Computational Technologies for Biomedical Research (Wiley, 2011):
Even within an institution — which should be legally, strategically, and financially incented for alignment, and for maximizing the opportunities for internal collaboration — barriers still exist. The subunits of the institution: its departments, its divisions, its components produce collaboration “walls” of varying substantiality. Organizational lore and personal relationships add another layer of “not-invented here” (NIH) culture, and allegiances to local agendas, even to the point of disadvantaging the larger institutional unit. In fact, if we wish to pursue the elimination of collaboration barriers we have to realize that many barriers are not institutional at all. Choices to collaborate or not collaborate are sometimes based not just on current affiliations but on past affiliations, degrees obtained, reputations, and even a less than rational bias as to just who our collaboration partners should be.